gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize the patient-specific neoantigen peptide–HLA class II complex via native TCRs and directly kill target cells through perforin/granzyme release and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD4+ TCR recognition; allele-restricted by patient HLA class II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06107894
disease_id_num_tar_ref
381
drug_id_num_tar_ref
1068