gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered TCR-T cells recognize HBV peptide–HLA-A*02:01 on target cells and induce MHC I–restricted killing via perforin/granzyme-mediated apoptosis (and Fas–FasL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC class I peptide–HLA (pMHC) complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06885710
disease_id_num_tar_ref
4392
drug_id_num_tar_ref
11894