gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific binds the tumor-associated antigen on target cells and CD3 on T cells, forming an immune synapse; engaged T cells kill antigen-positive cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-cell antigen bound by the second arm; not specified in the trial record
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06412471
disease_id_num_tar_ref
389
drug_id_num_tar_ref
1093