gene_symbol
TACSTD2
hgnc_id
HGNC:11530
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-NK cells recognize Trop-2 on target cells and kill them via antigen-dependent activation with perforin/granzyme-mediated cytotoxicity (with cytokine release).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Extracellular domain of a cell-surface transmembrane glycoprotein overexpressed on NSCLC
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06454890
disease_id_num_tar_ref
4479
drug_id_num_tar_ref
12099