gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-targeted CAR T cells bind BCMA+ cells, activate, and kill them via perforin/granzyme-mediated cytolysis and apoptotic pathways (e.g., Fas/FasL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
BAFF/APRIL-binding TNFRSF receptor on plasmablasts/plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06794008
disease_id_num_tar_ref
4547
drug_id_num_tar_ref
12278