gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-directed CAR-T cells bind BCMA on target cells, activate, and kill via perforin/granzyme-mediated cytolysis (and Fas–FasL apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
membrane-bound cell-surface receptor on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06581640
disease_id_num_tar_ref
4556
drug_id_num_tar_ref
12303