gene_symbol
CD79B
hgnc_id
HGNC:1699
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD79b on malignant B cells via the CAR and directly lyse them through T-cell effector mechanisms (perforin/granzyme and death-receptor pathways) upon engagement.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Targeted by bivalent/dual-antigen CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06026319
disease_id_num_tar_ref
4577
drug_id_num_tar_ref
12372