gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CD3 is on T cells and is used to engage and activate them; the activated T cells kill BCMA-positive tumor cells via immune synapse formation and perforin/granzyme release. CD3+ cells themselves are not targeted for lysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD3 complex on T cells; specific subunit not specified
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06100237
disease_id_num_tar_ref
4586
drug_id_num_tar_ref
12393