gene_symbol
UNKNOWN
binding_type
other
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The antibody’s Fc binds Fcγ receptors on effector cells (e.g., NK cells, macrophages) to trigger ADCC/ADCP against CTLA-4-expressing Tregs; FcγR-positive cells are effectors, not killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Fc-mediated engagement for effector functions (e.g., Treg depletion)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06589440
disease_id_num_tar_ref
4613
drug_id_num_tar_ref
12475