gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize the patient-specific neoantigen peptide–HLA class I complex via native TCRs and directly induce apoptosis via perforin/granzyme (and Fas–FasL) cytotoxic pathways.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–HLA class I (HLA-A/B/C; patient-specific allele) recognized by CD8+ TCRs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06532812
disease_id_num_tar_ref
4652
drug_id_num_tar_ref
12571