gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific engages CD3 on T cells to activate and redirect them to kill CD20+ B cells via immune synapse formation and perforin/granzyme-mediated cytotoxicity; CD3+ T cells themselves are not targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Effector engagement target; exact subunit not specified in trial record
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06318884
disease_id_num_tar_ref
4666
drug_id_num_tar_ref
12617