gene_symbol
GPRC5D
hgnc_id
HGNC:13310
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind GPRC5D on target cells, form an immunologic synapse, and kill via perforin/granzyme-mediated apoptosis (with T-cell activation and cytokine release).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface GPCR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05980507
disease_id_num_tar_ref
4683
drug_id_num_tar_ref
12665