gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Dual CAR-T cells recognize BCMA on target cells and, upon CAR signaling, directly kill them via T-cell effector mechanisms (perforin/granzyme release and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen on plasma cells; target of one CAR module in dual-target product
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05840107
disease_id_num_tar_ref
4693
drug_id_num_tar_ref
12696