gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CMV-specific donor T cells recognize the pp65 peptide–MHC I complex via their native, HLA-restricted TCRs and kill infected cells through CD8+ perforin/granzyme-mediated cytotoxicity (with CD4+ helper support).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide derived from CMV pp65 presented by HLA class I on infected host cells; recognized by CD8+ TCRs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06011486
disease_id_num_tar_ref
4735
drug_id_num_tar_ref
12802