gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize the tumor-associated surface antigen and directly kill antigen-positive cells via T-cell effector functions (perforin/granzyme-mediated apoptosis and death-receptor signaling) after CAR activation.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target varies by CAR-T product; common hematologic targets include CD19 (CD19) and BCMA (TNFRSF17), among others.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06350994
disease_id_num_tar_ref
4745
drug_id_num_tar_ref
12824