gene_symbol
MUC16
hgnc_id
HGNC:15582
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific MUC16×CD3 antibody crosslinks T cells to MUC16+ cells, activating T cells to deliver perforin/granzymes and lyse the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as CA-125 (cancer antigen 125)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06444880
disease_id_num_tar_ref
4760
drug_id_num_tar_ref
12869