gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Reinfused TILs recognize the neoantigen peptide–MHC-I via native TCRs and directly kill target cells through cytotoxic T-cell mechanisms (perforin/granzyme-mediated apoptosis, Fas–FasL).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognized by CD8+ TIL TCRs; allele-restricted (e.g., HLA-A/B/C)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05971589
disease_id_num_tar_ref
4800
drug_id_num_tar_ref
12957