gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize the shared tumor-associated antigen peptide presented on HLA class I via native TCRs and directly kill the presenting cells through perforin/granzyme cytolysis (and Fas–FasL apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognized by CD8+ TIL TCRs; allele-restricted (e.g., HLA-A/B/C); categories include differentiation and cancer-testis antigens
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05971589
disease_id_num_tar_ref
4800
drug_id_num_tar_ref
12957