gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize the peptide–HLA class II complex via native CD4+ TCRs and directly kill target cells through perforin/granzyme (and Fas–FasL) cytotoxic pathways.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognized by CD4+ TIL TCRs; allele-restricted (e.g., HLA-DR/DP/DQ)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05971589
disease_id_num_tar_ref
4800
drug_id_num_tar_ref
12957