gene_symbol
MICB
hgnc_id
HGNC:7091
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CIK cells recognize MICB via NKG2D, triggering direct tumor cell killing through perforin/granzyme release and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand; stress-induced
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06389305
disease_id_num_tar_ref
4802
drug_id_num_tar_ref
12963