gene_symbol
ULBP5
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CIK cells express NKG2D, which binds ULBP5 on target cells and triggers MHC-unrestricted cytotoxicity via perforin/granzyme release and Fas/FasL interactions.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06389305
disease_id_num_tar_ref
4802
drug_id_num_tar_ref
12963