gene_symbol
FAS
hgnc_id
HGNC:11920
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CIK cells express Fas ligand (FasL) that binds Fas (CD95) on target cells, triggering extrinsic apoptosis (death receptor–caspase pathway); they can also kill via perforin/granzyme.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Death receptor engaged by Fas ligand (FASLG) on CIK cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06389305
disease_id_num_tar_ref
4802
drug_id_num_tar_ref
12963