gene_symbol
CD5
hgnc_id
HGNC:1685
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD5 on target cells, forming an immune synapse and inducing perforin/granzyme-mediated cytolysis (and death receptor pathways), killing CD5+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen expressed on malignant and normal T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06633341
disease_id_num_tar_ref
4831
drug_id_num_tar_ref
13043