gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize the patient-specific neoantigen peptide–HLA class II complex via native TCRs and directly kill antigen-positive tumor cells through cytolytic granule (perforin/granzyme) release and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
peptide–MHC class II; CD4+ T-cell recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06235242
disease_id_num_tar_ref
4845
drug_id_num_tar_ref
13075