gene_symbol
IL3RA
hgnc_id
HGNC:6012
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered NK cells bind CD123 on target cells and directly kill them via perforin/granzyme degranulation and death-receptor–mediated apoptosis (e.g., FasL/TRAIL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06690827
disease_id_num_tar_ref
4860
drug_id_num_tar_ref
13109