gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells recognize CD20 via the CAR, triggering CD3zeta/costimulatory signaling and T-cell effector functions (perforin/granzyme release and Fas–FasL interactions) to kill the target cell.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; targeted by dual CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06295549
disease_id_num_tar_ref
4867
drug_id_num_tar_ref
13123