gene_symbol
TACSTD2
hgnc_id
HGNC:11530
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-NK cells recognize TROP2 on target cells, triggering NK activation and degranulation with perforin/granzyme–mediated cytolysis (and death-receptor signaling), killing TROP2-positive cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor cell-surface antigen targeted by CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05922930
disease_id_num_tar_ref
4873
drug_id_num_tar_ref
13136