gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-specific CAR T cells recognize BCMA on target cells and directly kill them via perforin/granzyme-mediated cytolysis and apoptosis (and Fas–FasL signaling).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Plasma cell surface receptor (TNFRSF)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06435897
disease_id_num_tar_ref
4874
drug_id_num_tar_ref
13140