gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific T‑cell engager links CD3 on T cells to DLL3 on target cells, forming an immune synapse that activates T cells to release perforin/granzymes and kill DLL3-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Notch pathway ligand on tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05916313
disease_id_num_tar_ref
4905
drug_id_num_tar_ref
13228