gene_symbol
CD79B
hgnc_id
HGNC:1699
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD79b CAR T cells bind CD79b on target B cells, become activated, and kill them via perforin/granzyme–mediated cytotoxicity (with apoptosis of CD79b-positive cells).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell receptor complex subunit; cell-surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05773040
disease_id_num_tar_ref
4908
drug_id_num_tar_ref
13233