gene_symbol
CTAG1A
hgnc_id
HGNC:24198
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused autologous T cells use native, MHC-restricted TCRs to recognize NY-ESO-1–derived peptides on tumor MHC and kill target cells via perforin/granzyme-mediated cytolysis (with supporting cytokine-driven activation).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
MHC-restricted TCR recognition of peptide epitopes; class I and II depending on clone
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06549751
disease_id_num_tar_ref
427
drug_id_num_tar_ref
1206