gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD38 on target cells and induces killing via Fc-mediated ADCC, complement-dependent cytotoxicity, antibody-dependent phagocytosis, and can also directly trigger apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Binding inhibits CD38 ectoenzyme (ADP-ribosyl cyclase/cADPR hydrolase) activity
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05669989
disease_id_num_tar_ref
4918
drug_id_num_tar_ref
13258