gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 mAb binds CD20 on B cells and triggers killing via Fc-mediated ADCC by NK/macrophages, complement-dependent cytotoxicity (CDC), and apoptosis of the bound cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Conformational epitope on the large extracellular loop (Type I anti-CD20)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05906992
disease_id_num_tar_ref
4950
drug_id_num_tar_ref
13348