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gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Mosunetuzumab engages CD3 on T cells to redirect their cytotoxicity toward CD20+ B cells; T cells (CD3ε+) are not the killed cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor/CD3 complex component
trial_id_tar_ref
drug_id_tar_ref
nct_id_tar_ref
NCT05886036
disease_id_num_tar_ref
4964
drug_id_num_tar_ref
13380