gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Mosunetuzumab binds CD20 on target cells and CD3 on T cells, bringing them together to form an immune synapse and activate T cells to kill CD20+ cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell differentiation antigen on malignant and normal B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06090539
disease_id_num_tar_ref
4971
drug_id_num_tar_ref
13414