gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize the neoantigen peptide–MHC I complex via their native TCR and directly lyse target cells through perforin/granzyme release (and Fas–FasL pathways).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Patient-specific peptide–MHC I complexes recognized by CD8+ TILs; polyclonal TCR repertoire
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06334783
disease_id_num_tar_ref
4989
drug_id_num_tar_ref
13464