gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Reinfused TILs recognize tumor-associated peptide–HLA class I complexes via their native TCRs and directly kill target cells through perforin/granzyme-mediated apoptosis (and Fas–FasL), with cytokines supporting cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Non-mutated TAA-derived peptide–MHC I complexes on tumor cells; CD8+ TIL recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06334783
disease_id_num_tar_ref
4989
drug_id_num_tar_ref
13464