gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-targeted CAR T cells bind BCMA on target cells, activate, and kill them via perforin/granzyme-mediated cytolysis (apoptosis) after immunologic synapse formation.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor on plasma cells; HLA-independent CAR binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06464991
disease_id_num_tar_ref
5010
drug_id_num_tar_ref
13540