gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Blinatumomab binds CD3ε on T cells to activate and redirect them to kill CD19+ B cells; it does not kill CD3-expressing T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Component of CD3/TCR complex on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06658938
disease_id_num_tar_ref
5014
drug_id_num_tar_ref
13548