gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti‑CD20 IgG1 binds CD20 on B cells and triggers Fc‑mediated ADCC (NK cells/macrophages), complement‑dependent lysis (CDC), and some direct apoptosis via CD20 crosslinking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type I anti-CD20 monoclonal antibody
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06186648
disease_id_num_tar_ref
5018
drug_id_num_tar_ref
13561