gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Transferred TILs recognize the patient-specific neoantigen peptide–HLA class I complex via their native TCRs and directly kill the presenting cells through perforin/granzyme-mediated cytolysis (and Fas–FasL/apoptotic pathways).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ TCR recognition; typically HLA-A/B/C restricted
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05903937
disease_id_num_tar_ref
5046
drug_id_num_tar_ref
13641