gene_symbol
ULBP4
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D-CAR T cells bind ULBP4 on target cells, become activated, and kill the engaged cells via perforin/granzyme-mediated cytotoxicity (with associated cytokine release).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
stress-induced NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06509490
disease_id_num_tar_ref
436
drug_id_num_tar_ref
1232