gene_symbol
RAET1L
hgnc_id
HGNC:16798
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D CAR T cells bind ULBP6 on target cells, activating CD3ΞΆ/4-1BB signaling and inducing perforin/granzyme-mediated lysis with cytokine release.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
stress-induced NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06509490
disease_id_num_tar_ref
436
drug_id_num_tar_ref
1232