gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD19 via the CAR; antigen engagement activates the T cell to form an immunologic synapse and kill CD19+ cells via perforin/granzyme release (and death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface marker
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06298266
disease_id_num_tar_ref
441
drug_id_num_tar_ref
1242