gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-engineered double-negative T cells bind CD19 on target cells and induce cytotoxicity via immune synapse formation with perforin/granzyme-mediated apoptosis (and Fas–FasL pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen on B-lineage cells and plasmablasts
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06316076
disease_id_num_tar_ref
5116
drug_id_num_tar_ref
13860