gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific T‑cell engager links CD3 on T cells to CD20 on target cells, activating TCR signaling; engaged T cells kill CD20+ cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
2:1 bispecific format with bivalent CD20 binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05806099
disease_id_num_tar_ref
5148
drug_id_num_tar_ref
13950