gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-specific CAR-γδ T cells bind CD19 on target cells and, upon CAR signaling, induce MHC-independent killing via perforin/granzyme-mediated cytolysis and cytokine release.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
FMC63 scFv epitope on extracellular CD19
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06696833
disease_id_num_tar_ref
5174
drug_id_num_tar_ref
14032