gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD20 on B cells and triggers antibody-dependent cellular cytotoxicity via FcγR-expressing effector cells, complement-dependent cytotoxicity/lysis, and can induce apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type I anti-CD20 mAb; binds a discontinuous epitope in the large extracellular loop
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06700798
disease_id_num_tar_ref
5175
drug_id_num_tar_ref
14036