gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The drug binds CD3 on T cells to recruit and activate them against CD20+ B cells; activated T cells kill the CD20-expressing targets (perforin/granzyme), not the CD3+ T cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor-CD3 complex component on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06006117
disease_id_num_tar_ref
5177
drug_id_num_tar_ref
14041