gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize CD19, become activated via CD3zeta/co-stimulatory signaling, and kill target cells through perforin/granzyme release and death-receptor (e.g., Fas/FasL) pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Dual-targeting CAR product (CD19/CD22)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05168748
disease_id_num_tar_ref
5180
drug_id_num_tar_ref
14056